ΨBioBody OSNervous system ↗

BRAIN & NERVES / 01

A distributed network,
not brain alone.

Brain and spinal circuits integrate signals, peripheral nerves carry information in both directions, autonomic and enteric circuits regulate organs, and glia, vessels, immune cells, and endocrine loops shape the operating environment.

01CENTRAL INTEGRATION
01

Cerebral networks

Cortical and subcortical circuits support perception, action, language, memory, prediction, emotion, and flexible behavior. Functions emerge from networks rather than one isolated “center.”

02

Diencephalic relays

Thalamic circuits route and shape information; hypothalamic networks integrate temperature, appetite, osmolality, endocrine, autonomic, sleep, and defensive responses.

03

Brainstem control

Midbrain, pons, and medulla contain sensory, motor, arousal, respiratory, cardiovascular, cranial-nerve, and pain-modulating circuits.

04

Spinal processing

The spinal cord relays ascending and descending signals while local circuits organize reflexes, locomotor patterns, autonomic output, and sensory gating.

02PERIPHERAL INPUT AND OUTPUT
05

Sensory afferents

Receptors transduce touch, stretch, temperature, chemicals, tissue threat, position, and organ state into neural signals traveling toward central circuits.

06

Somatic motor output

Upper and lower motor pathways recruit skeletal-muscle motor units; sensory feedback continuously updates force, balance, and movement.

07

Autonomic output

Sympathetic and parasympathetic pathways use ganglia and organ-specific patterns to regulate smooth muscle, cardiac tissue, glands, vessels, and metabolism.

08

Enteric circuits

Networks within the gut coordinate motility, secretion, blood flow, and local sensation while communicating with central, autonomic, endocrine, immune, and microbial systems.

03SUPPORT, BARRIERS, AND FEEDBACK
09

Glia maintain context

Astrocytes, oligodendrocytes, Schwann cells, microglia, and other support cells manage ions, transmitters, myelin, metabolism, repair, and immune surveillance.

10

Barriers regulate exchange

Brain endothelium, pericytes, glial endfeet, meninges, and cerebrospinal-fluid interfaces control transport and protect neural extracellular conditions.

11

Endocrine loops extend time

Hypothalamic–pituitary axes convert neural context into circulating hormone signals with feedback spanning minutes to days.

12

Plasticity changes the map

Synapses, myelin, excitability, gene expression, glial state, and behavior adapt with learning, development, injury, sleep, and repeated experience.